There is a total of 2340 clues beginning with up
- Up-and-down, as a relationship
- Up-and-___
- Up-and-___ (future stars)
- Up-and-___ (promising rookie)
- Up-coming connection
- Up-coming connector
- Up-coming link
- Up-coming world phenomenon?
- Up-country
- Up-creek necessity
- Up-down connector
- Up-down places at school
- Up-ends
- Up-front
- Up-front alternative to a student loan?
- Up-front amount
- Up-front amount, in poker
- Up-front business funding
- Up-front charge
- Up-front fee
- Up-front group of seats
- Up-front guy for the RR?
- Up-front material
- Up-front money
- Up-front money, as for a car
- Up-front part of a shoe
- Up-front payment
- Up-front payments
- Up-front people
- Up-front poker money
- Up-front poker payment
- Up-front spot at the Met
- Up-front theater locale
- Up-good connection
- Up-in-smoke sound
- Up-in-the-air approx
- Up-in-the-air bear
- Up-in-the-air guess: Abbr
- Up-in-the-air no?
- Up-in-the-air toys
- Up-point link
- Up-river swimmer
- Up-scale items?
- Up-start?
- Up-tempo
- Up-tempo Caribbean dance
- Up-tempo instrumental style of jazz
- Up-tempo jazz genre
- Up-tempo jazz piano style
- Up-tempo jazz style
- Up-tempo music lover's aversion?
- Up-tempo musical pieces
- Up-tempo pieces?
- Up-the-river venue
- Up-tight
- Up-tight coiffure
- Up-to-date
- Up-to-date briefly
- Up-to-date "Great!"
- Up-to-date actor Carney?
- Up-to-date antelope?
- Up-to-date chap
- Up-to-date dressers
- Up-to-date fruit?
- Up-to-date in dress
- Up-to-date in style
- Up-to-date trollop?
- Up-to-date, circa '66
- Up-to-date, for Bruce?
- Up-to-date, for short
- Up-to-date, in a way
- Up-to-date, informally
- Up-to-date
- Up-to-date: Abbr
- Up-to-date: Fr
- Up-to-date: French
- Up-to-date: Prefix
- Up-to-date: Prefix
- Up-to-date; precisely
- Up-to-daters
- Up-to-no-goodniks
- Up-to-the-minute
- Up-to-the-minute information
- Up-to-the-minute men
- Up-to-the-minute news
- Up-to-the-minute, as news
- Up-to-the-minute
- Up-to-the-second
- Up-to-the-___
- Up-to-___
- Up
- Up/down dichotomy
- Up: 2 wds
- Up: Comb form
- Up: comb form
- Up: Dial
- Up: Prefix
- Up: Prefix
- Upas or yamanai
- Upas tree gum resin