There is a total of 4951 clues beginning with tw
- Two-time Time Man of the Year (and a hint to 17-, 27-, 41- and 54-Across)
- Two-time title role for Chris Hemsworth
- Two-time Tony winner Alfred
- Two-time Tony winner Bernadette
- Two-time Tony winner did a no-no
- Two-time Tony winner Finneran
- Two-time Tony winner George
- Two-time Tony winner Hagen
- Two-time Tony winner Judith
- Two-time Tony winner Minnelli
- Two-time Tony winner Patti
- Two-time Tony winner Rivera
- Two-time Tony-winner Jonathan
- Two-time Tony-winning actress Judith
- Two-time Tony-winning director McAnuff
- Two-time Tony-winning playwright Yasmina __
- Two-time Tour de France champ
- Two-time Triple Crown jockey
- Two-time Triple Crown jockey Arcaro
- Two-time Triple Crown winner
- Two-time U S Open winner Stewart
- Two-time US Open champ
- Two-time US Open champ Andre
- Two-time US Open champ Monica
- Two-time US Open champ of the 1990s
- Two-time US Open champ Stewart
- Two-time US Open champion
- Two-time US Open champion Ernie
- Two-time US Open golf champion
- Two-time US Open tennis champ
- Two-time US Open winner
- Two-time US Open winner Andre
- Two-time US Open winner Ernie
- Two-time US Open winner Fraser
- Two-time US Open winner Hart
- Two-time US Open winner Julius
- Two-time US Open winner Monica
- Two-time US Open winner Retief
- Two-time US Open winner Stewart
- Two-time US Open winner Tony
- Two-time US Open winner Trevino
- Two-time US Poet Laureate Howard
- Two-time US Women's Open champion
- Two-time US Women's Open golf champion
- Two-time US Women's Open winner
- Two-time US Women's Open winner Patty
- Two-time Ugandan coup victim
- Two-time US Open champ
- Two-time US Open Champion North
- Two-time US Open winner
- Two-time US Open winner Ernie
- Two-time US Open winner Monica
- Two-time US Women's Open golf champion Juli
- Two-time Venezuelan president Carlos
- Two-time victor over AES
- Two-time Wimbledon champ
- Two-time Wimbledon champ Edberg
- Two-time Wimbledon champ Goolagong
- Two-time Wimbledon champ Kvitová
- Two-time Wimbledon champ Murray
- Two-time Wimbledon champion
- Two-time Wimbledon winner
- Two-time Wimbledon winner Edberg
- Two-time Wimbledon winner Gibson
- Two-time Wimbledon winner Lew
- Two-time Wimbledon winner ___ Hoad
- Two-time winner of golf's Vardon Trophy
- Two-time winner of the Art Ross Trophy
- Two-time winner of the Best Adapted Screenplay Oscar
- Two-time winner of the Hart Trophy
- Two-time winner of the Masters
- Two-time winner of the Stalin Prize for literature
- Two-time winner of the Women's World Cup
- Two-time winner over 82-Down
- Two-time Winter Olympics city
- Two-time Winter Olympics host
- Two-time WNBA champion Montgomery
- Two-time WNBA champions from Seattle
- Two-time WNBA MVP Delle Donne
- Two-time WNBA MVP __ Delle Donne
- Two-time WNBA MVP ___ Delle Donne
- Two-time Women's Open champ
- Two-time Women's Open winner
- Two-time World Cup finals host
- Two-time world figure skating champ Slutskaya
- Two-time World Series champs
- Two-time World Series winner
- Two-time world skating champ Albright
- Two-timed
- Two-timer
- Two-timer's liaison
- Two-timer, eg
- Two-timer, say
- Two-timers
- Two-timers
- Two-times
- Two-timing
- Two-timing guy
- Two-timing rodents?
- Two-timing sort