There is a total of 4951 clues beginning with tw
- Two-time host of "The Tonight Show"
- Two-time host of the Olympics
- Two-time host of the Summer Olympics
- Two-time Hugo Award winner Gaiman
- Two-time Indian prime minister
- Two-time Indian Prime Minister Gandhi
- Two-time Indy 500 champ Luyendyk
- Two-time Indy 500 winner Luyendyk
- Two-time Indy 500 winner of the 1990s Luyendyk
- Two-time Indy champ Luyendyk
- Two-time Indy winner Luyendyk
- Two-time Irish political leader
- Two-time Israeli prime minister
- Two-time Italian prime minister
- Two-time Italian prime minister Aldo
- Two-time Italian prime minister Giuliano
- Two-time Italian prime minister Moro
- Two-time Jack Nicklaus Trophy winner Jay
- Two-time LPGA champ born in Korea
- Two-time LPGA Championship winner Laura
- Two-time Latin Pop Grammy winner Jon
- Two-time link
- Two-time loser of the '50s, initially
- Two-time loser to 90-Down
- Two-time loser to Ali
- Two-time loser to DDE
- Two-time loser to DDE
- Two-time loser to Dwight
- Two-time loser to Ike
- Two-time loser to McKinley
- Two-time losing Republican presidential candidate
- Two-time lower to Ike
- Two-time Masters champ
- Two-time Masters champ Ballesteros
- Two-time Masters champ Watson
- Two-time Masters champion
- Two-time Masters champion Watson
- Two-time Masters winner Ballesteros
- Two-time Masters winner Bernhard
- Two-time Masters winner Nick
- Two-time Mexican president
- Two-time middleweight champ
- Two-time MLB all-star Ron
- Two-time movie
- Two-time movie role for Dana
- Two-time MVP quarterback
- Two-time mythological role for Anthony Hopkins
- Two-time NBA All-Star Brand
- Two-time NBA All-Star Robinson
- Two-time NBA MVP Steve
- Two-time NL batting champ Lefty
- Two-time NL batting champ Richie
- Two-time NL batting champ Willie
- Two-time NL MVP, 1954 and 1965
- Two-time NAACP Image award-winning actor
- Two-time NASCAR champion Jarrett
- Two-time Nascar Cup Series champ Busch
- Two-time National Book Award-winning poet AR __
- Two-time National League batting champ Lefty
- Two-time National League MVP
- Two-time National League MVP Murphy
- Two-time National League MVP, in 1954 and 1965
- Two-time national ticket candidate
- Two-time NBA All-Star Game MVP
- Two-time NBA all-star Vandeweghe
- Two-time NBA champ Lamar
- Two-time NBA Coach of the Year
- Two-time NBA Finals MVP
- Two-time NBA Finals MVP Kevin
- Two-time NBA MVP
- Two-time NBA MVP Curry
- Two-time NBA MVP Karl
- Two-time NBA MVP Malone known as "The Mailman"
- Two-time NBA MVP Steve
- Two-time NBA scoring champ
- Two-time NBA scoring leader
- Two-time Newbery Award winner Lois
- Two-time Newbery Medal winner Lowry
- Two-time Newbery winner Lowry
- Two-time Newbery winner ___ Lowry
- Two-time NFL MVP
- Two-time NFL sacks leader __ Allen
- Two-time NHL Norris Trophy winner Karlsson
- Two-time Nicaraguan president Chamorro
- Two-time Nobel Prize winner
- Two-time Nobel recipient Curie
- Two-time Nobelist
- Two-time Nobelist Curie
- Two-time Nobelist Marie
- Two-time Nobelist Pauling
- Two-time Nobelist physicist
- Two-time Nobelist, formally
- Two-time NOW president
- Two-time NOW president Eleanor
- Two-time Olivier Award winner Jacobi
- Two-time Olympic decathlon champ/California congressman, 1967-75
- Two-time Olympic gold medalist in soccer
- Two-time Olympic ice-skating medalist Brian
- Two-time Olympic pairs figure skating gold medalist Protopopov
- Two-time Olympic running gold medalist ___ Gebrselassie