There is a total of 85689 clues beginning with o
- One of two components of the drug Sinemet
- One of two countries with a square flag
- One of two Crayola colors with the shortest name
- One of two decisive games
- One of two definitive proposal responses
- One of two definitive responses
- One of two deliveries?
- One of two directing brothers
- One of two Disney characters singing "For the First Time in Forever"
- One of two Doberman pinschers on "Magnum, PI"
- One of two domesticated insects
- One of two dozen in the body
- One of two drawn in "Hangman"
- One of two dukes
- One of two elements that ends with the letter C
- One of two elimination games
- One of two engineering features depicted in this puzzle
- One of two English queens
- One of two equal parts
- One of two equal portions
- One of two events a year
- One of two evils
- One of two extra cards in a deck
- One of two extremes: Abbr
- One of two famous defendants
- One of two Fido feet
- One of two figures in "The Wizard of Oz"
- One of two for a buck?
- One of two for a downhill run
- One of two for a female kangaroo, surprisingly
- One of two for a positive number
- One of two for a tee
- One of two for a Valkyrie's horse
- One of two for four
- One of two for Linus Pauling
- One of two for Marie Curie
- One of two for the Ten Commandments
- One of two found in mezzanines?
- One of two global zones
- One of two gridiron borders, and what the last words of 17-, 23-, 52- and 62-Across can have
- One of two Halloween options
- One of two Hangman lines
- One of two hardy followers
- One of two Harrison compositions on the Beatles' "Let It Be"
- One of two heard in America
- One of two hogged by a road hog
- One of two identical genetic strands
- One of two identical people
- One of two in "Alabama"
- One of two in "boxcars"
- One of two in "Eddie Izzard"
- One of two in "épée"
- One of two in "George"
- One of two in "Hamilton"
- One of two in "Hamlet" or three in "Macbeth"
- One of two in "résumé"
- One of two in "The Grapes of Wrath"
- One of two in "The Help"
- One of two in "The Twelve Days of Christmas"
- One of two in "Waiting for Godot"
- One of two in 'crocus'
- One of two in 12
- One of two in 27-Down: Abbr
- One of two in a 47-Across
- One of two in a 747
- One of two in a barbecue tool
- One of two in a bassoon
- One of two in a Big Mac
- One of two in a bow knot
- One of two in a boxing ring
- One of two in a Canadian puzzle
- One of two in a cassette
- One of two in a Christmas song
- One of two in a conflict
- One of two in a crash
- One of two in a dance name
- One of two in a dead man's hand
- One of two in a double vanity
- One of two in a football game
- One of two in a friendly "bump"
- One of two in a Frost poem
- One of two in a game
- One of two in a game, perhaps
- One of two in a historic 1869 Utah meeting
- One of two in a hockey game
- One of two in a jack-o'-lantern?
- One of two in a plane
- One of two in a right triangle
- One of two in a row
- One of two in a rumba
- One of two in a score
- One of two in a Social Security number
- One of two in a split
- One of two in a sporting event
- One of two in a tournament
- One of two in a typical musical
- One of two in a typical string octet
- One of two in Albee's "Three Tall Women"
- One of two in an American puzzle
- One of two in an English horn