There is a total of 6259 clues beginning with is
- Isle in famous a palindrome
- Isle in Firth of Clyde
- Isle in Irish Sea
- Isle in N Y Harbor
- Isle in Taiwan Strait
- Isle in the Aegean
- Isle in the Bay of Naples
- Isle in the English Channel
- Isle in the Irish Sea
- Isle in the Irish Sea
- Isle invaded by MacArthur
- Isle just north of Haiti
- Isle known as "The Gathering Place"
- Isle N of Zanzibar
- Isle named for a Gaelic goddess
- Isle near Aruba
- Isle near Corsica
- Isle near Cura?ao
- Isle near CuraƧao
- Isle near Java
- Isle near Java
- Isle near Mull
- Isle near Naples
- Isle near Naxos
- Isle near Oahu
- Isle near Scotland
- Isle near Sorrento
- Isle near St Christopher
- Isle near Venezuela
- Isle not far from Naples
- Isle now part of Cambridgeshire
- Isle of 1814 exile
- Isle of 2 sq mi in the English Channel
- Isle of an exile
- Isle of Arthurian legend
- Isle of Bay of Naples
- Isle of Britain
- Isle of broguery
- Isle of Capri attraction
- Isle of dancers
- Isle of Donegal
- Isle of E England
- Isle of exile
- Isle of exile for Napoleon
- Isle of exile
- Isle of Hawaii
- Isle of Kwajalein atoll
- Isle of Man denizen
- Isle of Man judge
- Isle of Man locale
- Isle of Man location
- Isle of Man man
- Isle of Man man, for example
- Isle of Man man
- Isle of Man men
- Isle of Man men, eg
- Isle of Man men
- Isle of Man native
- Isle of Man resident
- Isle of Man residents
- Isle of Man setting
- Isle of Man surrounder
- Isle of Man's House of ___
- Isle of Man's locale
- Isle of Man's sea
- Isle of Man's surroundings
- Isle of Man's waterfront
- Isle of Man's waters
- Isle of Man: anc name
- Isle of Minos
- Isle of Mull neighbor
- Isle of myth
- Isle of Napoleon
- Isle of Napoleon's exile
- Isle of note
- Isle of Pines
- Isle of poetry
- Isle of Q "Bag of ___"
- Isle of retreat
- Isle of romance
- Isle of Scotland's Inner Hebrides
- Isle of Skye natives
- Isle of song
- Isle of song
- Isle of St John the Divine
- Isle of the Carolines
- Isle of the Cyclades
- Isle of the disarmed lady
- Isle of the Hebrides
- Isle of the Inner Hebrides
- Isle of the Labyrinth
- Isle of the Manx-men
- Isle of the Manxmen
- Isle of the oracle
- Isle of the ___
- Isle of Venus
- Isle of Wight channel
- Isle of Wight channel
- Isle of Wight location
- Isle of Wight resort