There is a total of 6259 clues beginning with is
- Is an opposite?
 - Is an ordeal
 - Is an usher
 - Is an utter failure
 - Is angry
 - Is angry
 - Is anguished over a decision
 - Is annoyed at
 - Is annoying
 - Is annoyingly slow, as an internet connection
 - Is another way?
 - Is anxious
 - Is apathetic
 - Is apathetic
 - Is apparent
 - Is apparent
 - Is apparently
 - Is appealing
 - Is appealing?
 - Is apprehensive about
 - Is apprehensive of
 - Is apprehensive
 - Is appropriate
 - Is appropriate for
 - Is appropriately dressed
 - Is apropos
 - Is apt
 - Is apt (to)
 - Is apt to
 - Is around beforehand
 - Is around longer than
 - Is arrested, in slang
 - Is as stubborn as a mule
 - Is assured of success
 - Is astir with activity
 - Is aswarm
 - Is at a loss for words?
 - Is at an advantage
 - Is at fault
 - Is at hand
 - Is at odds with
 - Is at the end of one's rope?
 - Is at the Forum?
 - Is at the plate
 - Is attentive
 - Is attentive, in a way
 - Is attired in
 - Is attracted
 - Is attracted by
 - Is attracted by
 - Is attracted to
 - Is attracted to
 - Is attractive
 - Is attractive to
 - Is attributable (to)
 - Is audibly awed
 - Is audibly shocked
 - Is audibly sorrowful
 - Is audibly unhappy
 - Is authorized to
 - Is averse to
 - Is awarded
 - Is aware of
 - Is aware of, Scripturally
 - Is awesome
 - Is awful
 - Is awful, slangily
 - Is bad
 - Is bad for
 - Is bad, real bad
 - Is badly beaten
 - Is baffled by
 - Is based
 - Is bearish
 - Is bearish in Wall Street
 - Is bearish on Wall Street, perhaps
 - Is beaten by
 - Is bedbound
 - Is bedridden
 - Is bedridden, say
 - Is behind
 - Is behind financially
 - Is behind the wheel
 - Is behind, in a way
 - Is behind, perhaps
 - Is behindhand
 - Is beholden
 - Is beholden (to)
 - Is beholden to
 - Is beholden to
 - Is being equivocal
 - Is below par
 - Is below par, perhaps
 - Is beneficial
 - Is benumbed
 - Is beside
 - Is besotted by
 - Is bested
 - Is bested by
 - Is bested or worsted