There is a total of 6259 clues beginning with is
- Is very burdensome
- Is very conspicuous
- Is very dizzy
- Is very fond of
- Is very fond of (with "on")
- Is very fond of
- Is very fortunate, with "out"
- Is very sleepy
- Is very talented, before "him" or "her"
- Is very thorough (with 38-Across)
- Is very wary of
- Is very well-received
- Is vested (with "in")
- Is vested as a right
- Is vexed
- Is vexing
- Is vexing to
- Is vexing
- Is victorious
- Is victorious in
- Is victorious over
- Is victorious
- Is vigilant
- Is visibly curious
- Is visibly dejected
- Is visibly elated
- Is visibly frightened
- Is visibly miserable
- Is visibly thunderstruck
- Is wafted on the breeze
- Is wanting
- Is watchful
- Is wavering
- Is way cool
- Is way too introspective
- Is wearing
- Is wearing
- Is wearisome
- Is wearisome due to excess
- Is weary
- Is welcomed by the doorman
- Is well advised
- Is well suited to be a reporter
- Is well-camouflaged
- Is well-endowed?
- Is well-informed
- Is well-versed in a subject
- Is wide open
- Is wide open, as a chasm
- Is wild about
- Is wild for
- Is wildly unstable
- Is willing to
- Is willing to resolve things
- Is willingly up to no good
- Is winded
- Is wiped out
- Is wise to
- Is wishy-washy
- Is wistful (for)
- Is with you
- Is within earshot
- Is without
- Is without compare
- Is worried
- Is worried about
- Is worse than ever
- Is worth
- Is worth doing
- Is worth it
- Is worth it
- Is worth keeping, to Marie Kondo
- Is worth something, colloquially
- Is worth something, in dialect
- Is worthwhile
- Is worthwhile
- Is worthy
- Is worthy of
- Is worthy of a blessing?
- Is worthy of, as repeating
- Is written in old Rome?
- Is written on papyrus?
- Is wrong
- Is wrong
- Is yet to be decided
- Is yet to come
- Is zetetic
- Is __
- Is __ (probably will)
- Is __: imminently will
- Is __: likely will
- Is __: probably will
- Is ___ (probably will)
- Is ___ bird?
- Is ___ promise?
- Is ___ unto oneself
- Is, before
- Is, for Augustus
- Is, for many
- Is, for more than one