There is a total of 6259 clues beginning with is
- Is totally wrong?
- Is touching
- Is tough enough
- Is tractable
- Is transformed?
- Is treated fairly
- Is treated unfairly
- Is trepid
- Is tricked by
- Is triggered by
- Is troubled
- Is trying
- Is turbulent
- Is turned off by
- Is unable
- Is unable to
- Is unable to comprehend
- Is unable to cut the mustard
- Is unable to get away, say or a hint to 17-, 24- and 40-Across?
- Is unable to grasp, as a point
- Is unable to knit?
- Is unable to make a decision
- Is unable to pronounce the name of a deodorant brand?
- Is unable to quit
- Is unable to sign the top-billed star for an "Ocean's 13" sequel?
- Is unable to stand
- Is unable to stomach
- Is unable to tolerate
- Is unable
- Is unacceptable
- Is unavailing
- Is unbalanced
- Is unceratin, like a trumpeter?
- Is uncertain
- Is uncertain to, briefly
- Is unconcerned
- Is undecided
- Is undecided now
- Is under necessity (to)
- Is under new management
- Is under no obligation to
- Is under obligation
- Is under obligation to
- Is under obligation
- Is under the weather
- Is under, in corporate jargon
- Is underhanded
- Is undoubtedly
- Is unduly anxious
- Is unenthusiastic about
- Is unfairly critical
- Is unfazed
- Is ungenerous
- Is ungracious, in a way
- Is unintelligible
- Is unjustifiably critical
- Is unlike Peter Pan
- Is unobliged to
- Is unpleasant to recall
- Is unpleasantly suffused with
- Is unprepared
- Is unproductive
- Is unrequired to
- Is unresolved
- Is unruly in a crowd
- Is unruly in line
- Is unsatisfactory
- Is unsteady
- Is unsteady
- Is unsuccessful
- Is unsuccessful in
- Is untruthful
- Is untruthful with
- Is unused
- Is unused
- Is unusually bright
- Is unwelcome
- Is unwell
- Is unwilling to risk
- Is unwilling
- Is unwilling: Archaic
- Is up
- Is up against
- Is up against?
- Is up and about
- Is up on
- Is up to
- Is up to no good
- Is up to the task
- Is up, in a way
- Is up, in baseball
- Is up
- Is useful
- Is utterly inclined?
- Is vainly proud
- Is valued
- Is vanquished by
- Is venomous to
- Is venturesome
- Is very angry