There is a total of 6259 clues beginning with is
- Is recalcitrant
- Is reclusive
- Is recorded for posterity
- Is refluent
- Is reformed
- Is regretful about
- Is regretful of
- Is regretful
- Is regretting
- Is relative
- Is relative?
- Is relaxed
- Is relentlessly antagonistic
- Is relevant to
- Is remembered
- Is reminiscent of
- Is remiss
- Is remiss
- Is remorseful
- Is remorseful about
- Is repelled by
- Is repentant
- Is repentant of
- Is repulsed by
- Is repulsive
- Is repulsive, in a way
- Is required (to)
- Is required to
- Is resentful about
- Is resilient
- Is resistant to
- Is resolute
- Is resolved (to)
- Is respectful (to)
- Is respectful
- Is responsible for
- Is restless
- Is restrictive
- Is retrocessive
- Is revealed
- Is revived
- Is revolting
- Is revolting?
- Is rewarded for good planning
- Is rewarded for service
- Is rewarded for sowing
- Is rewarding
- Is rheumatic
- Is rife
- Is rife (with)
- Is right for
- Is right for the club
- Is right for the group
- Is right on the mark
- Is routed by
- Is routed by, say
- Is royalty
- Is rude to
- Is rude, in a way
- Is ruined
- Is ruled by
- Is saddled with
- Is salaried
- Is sans
- Is satisfied
- Is savory and then some
- Is scared of
- Is scared to go home?
- Is schneidered
- Is scintillating
- Is scornful of
- Is scrubbed clean, in some cases
- Is seconds behind
- Is sedentary
- Is seductive to
- Is seized of
- Is selective
- Is self-contained
- Is self-reproachful
- Is sensitive
- Is sent packing
- Is sentenced to
- Is serendipitous
- Is serious
- Is serious, or a hint to the end of each starred clue's answer
- Is seriously in doubt
- Is set
- Is severely affected: Colloq
- Is sharp with
- Is shellacked
- Is short
- Is short and shy
- Is short by
- Is short of
- Is short with
- Is short, in a way
- Is shown
- Is shown on TV
- Is shown, as a film
- Is shy