There is a total of 27405 clues beginning with fi
- First step
- First step for a would-be groom vis-à-vis his intended's father
- First step in a cleansing task
- First step in a hairdo
- First step in a progression
- First step in a series
- First step in addicts' treatment
- First step in division?
- First step in making a razor sharpener?
- First step of a contest
- First step of instructions for what to do with this finished puzzle
- First step of progress
- First step to riches?
- First step toward nirvana
- First step toward the Presidency for many
- First step's span
- First step
- First step?
- First Stephen King novel
- First steps
- First stock sale, for short
- First Stoic
- First stomach of a cow
- First stop for the rocket ship
- First strategy
- First strategy choice
- First streaker?
- First string
- First string?
- First stringers
- First stringers?
- First strip to win a Pulitzer
- First stroke
- First stroke for many
- First stroke setting
- First stroke, usually
- First strokes
- First Stuart king
- First stuff to learn
- First sub-Saharan country to obtain independence from colonial rule
- First subclause
- First subject in Euclid's "Elements"
- First substitute on a basketball bench
- First subway line in NYC
- First subway line in NYC
- First successful American automaker
- First successful video game
- First successfully mass-produced cars
- First suit?
- First sultan of both Syria and Egypt
- First Sum 41 hit
- First Super Bowl champs
- First Super Bowl MVP
- First Super Bowl MVP
- First Super Bowl played in prime time
- First Super Bowl rematch
- First Super Bowl that was actually called a Super Bowl
- First Super Bowl to be called "Super Bowl"
- First Super Bowl won by an African American coach
- First Super Bowl won by the AFL
- First Super Bowl won by the Giants
- First supermodel to produce her own posters and calendars
- First supersonic human
- First supreme commander of NATO
- First Supreme Court justice, alphabetically
- First survey datum, often
- First switch-hitter to win the Triple Crown, with 40-Across
- First Syd Barrett solo album
- First syllable in 2-Down, eg
- First syllable of a kids' menu game
- First syllable of a light-hearted refrain
- First syllable of a refrain
- First syllable of a rhyming film genre
- First syllable of a simple game
- First symbol on a music line
- First symbol on a musical staff
- First symptoms
- First symptoms, eg
- First synthetic dye
- First synthetic fiber
- First T in TNT
- First T Rex hit in 1970
- First takes
- First talkie star
- First talking pet in American comics
- First talking satellite, Dec 18, 1958
- First target of spaceships
- First Tarzan portrayer
- First tea sold in individual packets
- First team
- First team to appear on a 116 Across
- First team to go undercover?
- First team to play in a domed stadium
- First team to win five Super Bowls
- First telegrapher
- First temptation location
- First temptation site
- First ten US constitutional amendments
- First tennis player to earn $100,000 in one year