There is a total of 27411 clues beginning with fi
- First sentence of a news story
- First sequel to win Best Picture, with "The"
- First sequel's sequel
- First sergeant, in military slang
- First sergeant, informally
- First sergeant, slangily
- First sergeants, to GI's
- First served?
- First set of choices
- First set of circled letters
- First set of invitees
- First set of wheels, maybe
- First set of wheels, often
- First settled town in Maine
- First settlement in N E
- First settler
- First settlers
- First sgt, eg
- First Shaw play to be filmed
- First sheepkeeper
- First shepherd
- First shepherd in the Bible
- First shepherd
- First Sherlock Holmes book: 1887
- First Shia imam
- First ship builder
- First shot
- First shot at a corp's stock
- First shot, for many
- First shots in billiards
- First show
- First show to win 50 Emmys, in brief
- First showing
- First showing at a film festival in France?
- First showing at an all-day film festival? (1988)
- First showing of a film
- First showing, perhaps
- First showing
- First showings
- First shows
- First side to vote
- First sign
- First sign of a best seller
- First sign of a highway headache
- First sign of a shark
- First sign of failure
- First sign of fall
- First sign of rain
- First sign of spring
- First sign of spring?
- First sign of the zodiac
- First sign of the Zodiac
- First sign of zodiac
- First sign, astrologically
- First signer of the Declaration of Independence
- First signer of the Declaration of Independence: 2 wds
- First signs
- First signs of rain
- First signs of smoke
- First signs of spring
- First Sikh
- First silent film to win Best Picture since "Wings"
- First sin site
- First singer to have seven songs from a debut album chart on Billboard
- First singer to sell a million digital downloads in the first week
- First singer with a million-selling record
- First single by a rapper to reach #1 on the Billboard Hot 100
- First single released on Apple Records
- First single, often
- First sinner
- First Sister
- First sitcom episode
- First site of Olympic games
- First site of the Olympic Games
- First sitting president to have his photograph taken
- First sitting president to visit China
- First sitting president to visit the West Coast
- First sitting prez to fly in an airplane
- First six of 26
- First six tracks, say
- First skipper?
- First slayer
- First slight beginning
- First small bit of progress
- First small bite
- First Smashing Pumpkins single
- First Smashing Pumpkins video
- First snake spotter
- First soft drink sold in a can
- First soft drink sold in all-aluminum cans
- First Solo appearance
- First son
- First son of a President to become President
- First son of Eliz
- First son of Eliz II
- First son of Isaac
- First son of Seth
- First son of Seth, in Genesis
- First Son of the '80s
- First son of the third son