There is a total of 118044 clues beginning with f
- First sign of spring?
- First sign of the zodiac
- First sign of the Zodiac
- First sign of zodiac
- First sign, astrologically
- First signer of the Declaration of Independence
- First signer of the Declaration of Independence: 2 wds
- First signs
- First signs of rain
- First signs of smoke
- First signs of spring
- First Sikh
- First silent film to win Best Picture since "Wings"
- First sin site
- First singer to have seven songs from a debut album chart on Billboard
- First singer to sell a million digital downloads in the first week
- First singer with a million-selling record
- First single by a rapper to reach #1 on the Billboard Hot 100
- First single released on Apple Records
- First single, often
- First sinner
- First Sister
- First sitcom episode
- First site of Olympic games
- First site of the Olympic Games
- First sitting president to have his photograph taken
- First sitting president to visit China
- First sitting president to visit the West Coast
- First sitting prez to fly in an airplane
- First six of 26
- First six tracks, say
- First skipper?
- First slayer
- First slight beginning
- First small bit of progress
- First small bite
- First Smashing Pumpkins single
- First Smashing Pumpkins video
- First snake spotter
- First soft drink sold in a can
- First soft drink sold in all-aluminum cans
- First Solo appearance
- First son
- First son of a President to become President
- First son of Eliz
- First son of Eliz II
- First son of Isaac
- First son of Seth
- First son of Seth, in Genesis
- First Son of the '80s
- First son of the third son
- First son, often
- First son, sometimes
- First Song of the Year Grammy winner
- First Song of the Year Grammy winner (1958)
- First song on "More of the Monkees"
- First song on 22-Across
- First song on 32-Across
- First song on a CD
- First song on a John Lennon album of the same name
- First song on an album
- First song on Genesis's "Genesis" album
- First song on Radiohead's "OK Computer"
- First song on the Beatles' "White Album"
- First song parodied by Weird Al
- First sophomore to win the Heisman Trophy
- First soprano to star in "Turandot": 1926
- First sound in "Georgia"
- First sound in "GIF," some say
- First sound in an M-G-M film
- First sound in an MGM movie
- First sound in an SOS call
- First sound in MGM movies
- First sound of "gerbil" but not "goat"
- First sound of an MGM movie
- First sound of impact?
- First sound of silence?
- First sound of the day, for many
- First sound of work
- First sound-barrier breaker
- First source
- First South American city to host the Olympics
- First South Korean president
- First sovereign of Great Britain
- First Soviet leader
- First Soviet premier
- First space probe to enter Saturn's orbit
- First space tourist Dennis
- First space travelers
- First space travelers from US
- First spacecraft to orbit Jupiter
- First spacecraft to reach Uranus and Neptune
- First spaceman
- First spaceman's first name
- First spacewoman
- First Spaniard to cross the Mississippi
- First Spanish actor to win an Oscar
- First speaker in "Macbeth"
- First specimen of a new species