There is a total of 118044 clues beginning with f
- First Disney song to reach the top 5 on Billboard in the 21st century
- First distiller to sell whiskey by the bottle
- First division of an act
- First division, maybe
- First divorced US president
- First Dodge with front-wheel drive
- First Dodger in 1951 fold
- First Dog before Bo
- First dog in space
- First Dog of the 1940s
- First Dog of the forties
- First dog on an orbital spaceflight
- First dog to orbit Earth
- First dog walker, maybe
- First Dog, once
- First doll to be marketed as an “action figure”
- First domed ballpark
- First Dominican major-league manager
- First Dominican manager in MLB history
- First Dominican manager in the major leagues
- First Dominican-born Major League Baseball manager
- First donor?
- First dot-commer?
- First double Nobelist
- First double, and first female, Nobelist
- First double-digit number
- First down play
- First down yardage
- First down yardage
- First down?
- First Dr Kildare
- First Dracula of film
- First draft
- First draft of a 1995 De Niro/Pacino thriller?
- First draft picks
- First drafts
- First drawer of the Democratic donkey
- First drawing
- First drawing class, perhaps
- First Dreamliner buyer
- First drink ever ordered by James Bond
- First drink of hot coffee, eg
- First drug approved to treat AIDS
- First duke of Normandy
- First Dutch settlement in Java
- First dynamo developer
- First dynasty in China, c 2000 B C
- First Dynasty in Chinese history
- First dynasty in Chinese history
- First dynasty in traditional Chinese history
- First dynasty of China
- First dynasty of Chinese history
- First dynasty of imperial China, 221-206 BC
- First dynasty of Polish rulers
- First dynasty to unify China
- First Earl of Avon
- First Earl of Beaconsfield
- First Earl of Chatham
- First Earl of Chatham
- First Earl of Leicester
- First earring, maybe
- First earth orbiter
- First earthly garden
- First ed
- First edition, usually
- First editor of "The Overland Monthly"
- First editor of Ms
- First editor of the "Tatler"
- First editor of The Atlantic Monthly
- First editor of the magazine George
- First editor of The New Yorker
- First efforts at compromise
- First Egyptian king
- First Egyptian to win a Nobel Prize
- First elected Congresswoman Jeannette
- First elected governor of Alaska
- First elected governor of Alaska
- First elected member at Cooperstown
- First electronic computer
- First electronic computer, unveiled in 1946
- First electronic musical instrument
- First electronic stock market
- First elements
- First emergency craft captain
- First Emmy song hit: 1955
- First Emmy-winning song
- First emperor of Austria
- First emperor of Brazil
- First Emperor of Brazil, 1822–31
- First emperor of China
- First emperor of Rome
- First emperor of Rome
- First emperor of Russia
- First encounter in a romcom
- First English Channel swimmer
- First English child born in America
- First English child born in America
- First English colony in America
- First English commander to see the Pacific