There is a total of 118044 clues beginning with f
- First American canal
- First American canal
- First American carrier to show movies on flights
- First American college
- First American college to establish a university press
- First American college to go co-ed
- First American college to have an on-campus art museum
- First American college to win 100 NCAA titles
- First American college to win an intercollegiate football game
- First American color TV maker
- First American diplomat abroad
- First American executed for spying
- First American female astronaut
- First American film in which a toilet is heard being flushed (1960)
- First American hospital ship
- First American in orbit
- First American in space
- First American independent movie to get a Best Original Screenplay nomination
- First American literature Nobelist
- First American magazine to excerpt "Moby-Dick"
- First American minister to England
- First American movie to show a toilet flushing
- First American Nobelist for Literature
- First American orbiter
- First American Railway Union president
- First American Red Cross president Barton
- First American saint
- First American steam locomotive
- First American to orbit Earth
- First American to orbit the Earth
- First American to walk in space
- First American Tour de France winner Greg
- First American woman in space
- First American woman to win all-around gymnastics gold at the Olympics
- First among Italians
- First among men
- First among men?
- First among progeny
- First among siblings
- First among the children
- First among voyages
- First and 15th of each month, for some
- First and foremost
- First and foremost: Abbr
- First and last black key on a standard piano
- First and last digit in a Manhattan area code
- First and last name of an author
- First and last name of Rihanna
- First and last quarters, eg
- First and last word of a common four-word saw
- First and last word of a W S title
- First and last word of the Musketeers' motto
- First and last words of "Green Eggs And Ham"
- First and last
- First and only female Speaker of the House
- First and only fictional group to have a #1 hit song, with "The"
- First and only president of the Republic of Hawaii
- First and pocket
- First and reverse
- First and reverse, eg
- First and second
- First and second for example
- First and Second Avenues area, in Manhattan
- First and Second places?
- First and second, eg
- First and second, for two
- First and third
- First and third, eg
- First and worst tsar?
- First and __
- First and __: most important
- First and ___
- First and ___ (football term)
- First animal conservationist
- First animal in the Chinese zodiac
- First animal in the dictionary
- First animal of the Chinese zodiac
- First animal rescue vessel?
- First animal shelter
- First animal sound in "Old MacDonald"
- First animal up on the farm, usually
- First animal, in a way
- First animal?
- First animated dinosaur (1914)
- First animated film from DreamWorks
- First anniversary gift
- First anniversary gift for a zookeeper?
- First anniversary symbol
- First answer in the first-ever published crossword
- First anti-AIDS drug
- First antibacterial soap
- First antibacterial soap brand
- First antiparticle discovered
- First antiseptic surgeon
- First apartment, perhaps
- First ape trained to communicate with humans in sign language
- First appearance
- First appearance of Sid the sloth
- First appearance, as of dawn