The most common and most likely answer to this crossword clue is the 7 letter word PUBERTY which also is the latest solution we found used in LA Times in 2015.
Time for significant changes crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| PUBERTY | 100 % | 7 | 
Words with a meaning similar to the clue: Time for significant changes
These words may or may not be a possible solution to this crosswords clue.- change
 - era
 - transformation
 - ripe
 - age
 - epoch
 - upheavals
 - dislocation
 - turmoil
 - upheaval
 - diachronic
 - hour
 
Crossword Answer definitions
PUBERTY noun- A developmental phase brought about by the action of hormones as part of the maturing process. For humans, there are three in total.
 - The age at which a person is first capable of sexual reproduction.
 - The period when a plant begins to flower.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution