The most common and most likely answer to this crossword clue is the 3 letter word UFO which also is the latest solution we found used in New York Times in 2007.
Subject of many X-Files crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| UFO | 100 % | 3 | 
Words with a meaning similar to the clue: Subject of many X-Files
These words may or may not be a possible solution to this crosswords clue.- encyclopedia
 - impersonal
 - manifold
 - alien
 - ufo
 - thicket
 - canute
 - chapman
 - spinous
 - thorny
 - cases
 - issues
 
Crossword Answer definitions
UFO noun- A UFO.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution