The most common and most likely answer to this crossword clue is the 5 letter word AORTA which also is the latest solution we found used in LA Times in 2025.
Major vessel crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters |
|---|---|---|
| AORTA | 100 % | 5 |
Why may AORTA be the right solution?
The "AORTA" is a major blood vessel that carries oxygen-rich blood from the heart to the rest of the body. It is the largest artery in the body, making it a fitting answer for the clue "Major vessel."
Words with a meaning similar to the clue: Major vessel
These words may or may not be a possible solution to this crosswords clue.- aorta
- artery
- vasa vasorum
- anchor
- anchoring
- bowl
- captain
- cod
- crater
- dipper
- hold
- hull
Crossword Answer definitions
AORTA noun- The great artery which carries the blood from the heart to all parts of the body except the lungs; the main trunk of the arterial system.
- The liveliest part of something.
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution