The most common and most likely answer to this crossword clue is the 5 letter word AORTA which also is the latest solution we found used in LA Times in 2025.
Major artery crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters |
|---|---|---|
| AORTA | 94 % | 5 |
| CAROTID | 3 % | 7 |
| TURNPIKE | 1 % | 8 |
| FREEWAY | 1 % | 7 |
Why may AORTA be the right solution?
The answer to "Major artery" is "AORTA" because the aorta is the largest artery in the human body, carrying oxygenated blood from the heart to the rest of the body.
Words with a meaning similar to the clue: Major artery
These words may or may not be a possible solution to this crosswords clue.- vein
- aorta
- carotid
- freeway
- turnpike
- vasa vasorum
- arterial
- avenue
- iliac
- main
- area
- mainline
Crossword Answer definitions
AORTA noun- The great artery which carries the blood from the heart to all parts of the body except the lungs; the main trunk of the arterial system.
- The liveliest part of something.
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution
More clues leading to the result AORTA
- Central artery
- Main artery
- Main pipeline?
- Vital vessel
- Artery
- Blood line
- Main line
- Part of the circulatory system
- The main line
- Way from a man's heart
More clues leading to the result CAROTID
- Vital artery
- Jugular's counterpart
- Major artery
- Neck artery.
- Large artery.
- An artery.
- Artery of the head
- Neck artery
- Kind of artery
- ___ artery
More clues leading to the result TURNPIKE
- Pre-Interstate superhighway
- Major artery
- Toll road
- Highway.
- Motorway.
- Part of a pay-as-you-go plan?
- Expressway