The most common and most likely answer to this crossword clue is the 4 letter word OHIO which also is the latest solution we found used in New York Times in 2025.
Largest tributary of the Mississippi crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters |
|---|---|---|
| OHIO | 100 % | 4 |
Why may OHIO be the right solution?
The Ohio River is the largest tributary of the Mississippi River, making "OHIO" the correct answer.
Words with a meaning similar to the clue: Largest tributary of the Mississippi
These words may or may not be a possible solution to this crosswords clue.- ohio
- wisconsin
- missouri
- red
- rwd
- white
- yazoo
- minneapolis
- red river
- saint francis
- saint francis river
- st. francis
Crossword Answer definitions
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution