The most common and most likely answer to this crossword clue is the 7 letter word TENUITY which also is the latest solution we found used in Boston Globe in 2012.
Lack of substance crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| TENUITY | 100 % | 7 | 
Words with a meaning similar to the clue: Lack of substance
These words may or may not be a possible solution to this crosswords clue.- emptiness
 - void
 - vacuum
 - free space
 - empty space
 - vacuity
 - space
 - ether
 - in vacuo
 - vacuole
 - vanity
 - nothingness
 
Crossword Answer definitions
TENUITY noun- Thinness, slenderness.
 - Meagreness, paucity.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution