The most common and most likely answer to this crossword clue is the 6 letter word UNCLES which also is the latest solution we found used in New York Times in 2013.
Jesse and Leo of TV sitcoms crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| UNCLES | 100 % | 6 | 
Words with a meaning similar to the clue: Jesse and Leo of TV sitcoms
These words may or may not be a possible solution to this crosswords clue.- sam
 - ted
 - lucy
 - rob
 - fred
 - sara
 - susan
 - kate
 - dan
 - andy
 - censor
 - ida
 
Crossword Answer definitions
UNCLES noun- The brother or brother-in-law of one’s parent.
 - The male cousin of one’s parent.
 - A companion to one's (usually unmarried) mother.
 - A source of advice, encouragement, or help.
 - A pawnbroker.
 - An affectionate term for a man of an older generation than oneself, especially a friend of one's parents, by means of fictive kin.
 - An older male African-American person.
 
- To address somebody by the term uncle.
 - To act like, or as, an uncle.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution