The most common and most likely answer to this crossword clue is the 4 letter word IOTA which also is the latest solution we found used in Wall Street Journal in 2015.
Ithaka starts with one crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| IOTA | 100 % | 4 | 
Words with a meaning similar to the clue: Ithaka starts with one
These words may or may not be a possible solution to this crosswords clue.- shore
 - boot
 - center
 - lead
 - start
 - after
 - aggressor
 - apr
 - balloon
 - began
 - begin
 - beginner
 
Crossword Answer definitions
IOTA noun- The ninth letter of the Greek alphabet.
 - A jot; a very small, insignificant quantity.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution