The most common and most likely answer to this crossword clue is the 4 letter word ESAU which also is the latest solution we found used in USA Today in 2013.
Isaac's first crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters |
|---|---|---|
| ESAU | 100 % | 4 |
Words with a meaning similar to the clue: Isaac's first
These words may or may not be a possible solution to this crosswords clue.- abraham
- diplomacy
- esau
- inertia
- ike
- violin
- abram
- sarah
- eroded
- hayes
- mother
- shaft
Crossword Answer definitions
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution