The most common and most likely answer to this crossword clue is the 4 letter word RILE , but the solution may also be IRK which is one of the most recent solution (2025 in LA Times).
Irritate crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| RILE | 20 % | 4 | 
| ROIL | 8 % | 4 | 
| NETTLE | 7 % | 6 | 
| IRK | 7 % | 3 | 
| CHAFE | 7 % | 5 | 
| RASP | 7 % | 4 | 
| VEX | 6 % | 3 | 
| ANNOY | 4 % | 5 | 
| PEEVE | 4 % | 5 | 
| MIFF | 4 % | 4 | 
| RANKLE | 4 % | 6 | 
| PIQUE | 3 % | 5 | 
| TEASE | 2 % | 5 | 
| TEEOFF | 2 % | 6 | 
| GRATE | 2 % | 5 | 
| ABRADE | 1 % | 6 | 
| BUG | 1 % | 3 | 
| PROVOKE | 1 % | 7 | 
| GALL | 1 % | 4 | 
| EATAT | 1 % | 5 | 
| IRE | 1 % | 3 | 
| FRET | 1 % | 4 | 
| PESTER | 1 % | 6 | 
| EXACERBATE | 1 % | 10 | 
| BOTHER | 1 % | 6 | 
| RUFFLE | 1 % | 6 | 
| WEARON | 1 % | 6 | 
| INCENSE | 1 % | 7 | 
| RUBTHEYAWGNORW | 1 % | 14 | 
| ACERBATE | 1 % | 8 | 
| ANGER | 1 % | 5 | 
| GET | 0 % | 3 | 
| GETAT | 0 % | 5 | 
| BURNUP | 0 % | 6 | 
| RUBTHEWRONGWAY | 0 % | 14 | 
| NAG | 0 % | 3 | 
Why may VEX be the right solution?
The word "vex" means to irritate or annoy someone. Therefore, "vex" is the right answer to the clue "irritate."
Words with a meaning similar to the clue: Irritate
These words may or may not be a possible solution to this crosswords clue.- annoy
- rile
- vex
- bother
- rag
- nettle
- gravel
- devil
- get at
- get to
- nark
- irk
Crossword Answer definitions
RILE verb- To make angry
- To stir or move from a state of calm or order
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution
More clues leading to the result RILE
More clues leading to the result ROIL
More clues leading to the result NETTLE
- Irk
- Goad
- Harass
- Irritate
- Stinging plant
- Get under the skin of
- Plant with stinging leaves
- Plant with a sting
- Vex
- Herb with stinging hairs
More clues leading to the result IRK
More clues leading to the result CHAFE
- Rub
- Irritate
- Wear by rubbing
- Irritate in a way
- Rub annoyingly
- Rub the wrong way
- Abrade by rubbing
- React to wool, maybe
- Rub roughly
- Cause friction
More clues leading to the result RASP
- Coarse file
- File
- Grating sound
- Harsh sound
- Grate
- Not sound smooth
- Sound like Demi Moore or Marlene Dietrich
- Croak
- Farrier's tool
- Croaking voice
More clues leading to the result VEX
More clues leading to the result ANNOY
- Make hot under the collar
- Pester
- Slightly irritate
- Drive bonkers
- Bug
- Be on the back of
- Get under the collar of
- Be a pain in the neck
- Bother
- Irritate
More clues leading to the result PEEVE
More clues leading to the result MIFF
- Offend
- Annoy
- Cause annoyance
- Vex
- Give minor offense to
- Tick off
- Irritate
- Vex a bit
- Bend out of shape
- Make sore
More clues leading to the result RANKLE
- Irritate
- Annoy
- Fill with resentment
- Annoy no end
- Cause irritation
- Stick in one's craw
- Get one's goat
- Grate on
- Continue to irritate
- Fester in one's mind
More clues leading to the result PIQUE
- Arouse
- Snit
- Resentment
- Ill temper
- Excite, as interest
- Annoyance
- Engage, as interests
- Rouse
- Feeling of umbrage
- Arouse, as ire
More clues leading to the result TEASE
More clues leading to the result TEEOFF
- Get mad
- Drive on a course
- Hit one's drive
- Start a hole
- Hit a drive
- Start on the links
- Start the Masters
- Start golfing
- Irritate
- Start a round of golf
More clues leading to the result GRATE
- Prepare Parmesan
- Prepare the Romano
- Prepare Parmesan cheese
- Shred potatoes
- Furnace feature
- Rankle
- Get annoying
- Set teeth on edge
- Storm-drain cover
- Iron framework
More clues leading to the result ABRADE
- Rub
- Scrape
- Wear away
- Rub the wrong way?
- Use a pumice stone
- Wear down
- Chafe
- Irritate
- What a beard might do
- Wear by rubbing
More clues leading to the result BUG
- Glitch
- Listening device
- Annoy
- Common cold
- Pester
- Program problem
- Eavesdropper's aid
- Surveillance device
- Popular VW car
- Plant microphones
More clues leading to the result PROVOKE
More clues leading to the result GALL
- Impudent boldness
- Rub sore
- Saddle sore
- Nerve
- Unmitigated __
- Irk big-time
- Chutzpah
- Effrontery
- Some nerve
- Brazen boldness
More clues leading to the result EATAT
- Bug
- Vex
- "___ Joe's"
- Vex incessantly
- "__ Joe's"
- Bother over time
- Really bother
- Really irritate
- Nag, nag, nag
- __ home (dine in)
More clues leading to the result IRE
More clues leading to the result FRET
- Worry
- Guitar neck part
- Guitar part
- Fingerboard ridge
- Viol feature
- Neck division
- Neck line?
- Fender marking
- Neck line
- Neckline?
More clues leading to the result PESTER
More clues leading to the result EXACERBATE
More clues leading to the result BOTHER
- Fuss
- Take the trouble
- Get under the skin of
- Bug
- Trouble
- Annoy
- Pester
- Petty annoyance
- Inconvenience.
- Exclamation of mild vexation.
More clues leading to the result RUFFLE
- Petticoat feature
- Fashion frill
- Disturb
- Dust __
- Dress trimming
- Pinafore trim
- Irritate
- Perturb
- Clothing frill
- Drum sound
More clues leading to the result WEARON
- Annoy
- Elapse tediously
- Seem grating to
- Bore or burden
- Induce irritability
- Pass slowly, as time
- Pass slowly
- Irritate
- Become annoying to
- Make one tired
More clues leading to the result INCENSE
- Enrage
- Ceremonial odor
- Stuff burnt at church
- Pad perfume?
- Atmosphere enhancer
- You might deliberately burn it down
- Stick in a head shop
- Exasperate
- Smoke in a church
- Burn up
More clues leading to the result RUBTHEYAWGNORW
More clues leading to the result ACERBATE
More clues leading to the result ANGER
- Fit of temper
- Rage
- Breathe fire into
- Indignation
- Conniption cause
- Get one's dander up
- Provoke
- Tee off
- Possibly racist Depp movie Part II
- Fury
More clues leading to the result GET
- "__ lost!"
- "____ my drift?"
- Obtain
- Catch
- Come down with
- Pick up
- "___ Smart"
- Pay back
- Tennis retrieval
- "__ my drift?"