The most common and most likely answer to this crossword clue is the 8 letter word EPIDEMIC which also is the latest solution we found used in CrossSynergy in 2004.
Great Plague, eg crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| EPIDEMIC | 100 % | 8 | 
Words with a meaning similar to the clue: Great Plague, eg
These words may or may not be a possible solution to this crosswords clue.- epidemic
 - pepys
 - blast
 - curse
 - death
 - gout
 - infest
 - scourge
 - smite
 - torment
 - pestilence
 - bane
 
Crossword Answer definitions
EPIDEMIC noun- A widespread disease that affects many individuals in a population.
 - An occurrence of a disease or disorder in a population at a frequency higher than that expected in a given time period.
 
- Like or having to do with an epidemic; widespread
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution