The most common and most likely answer to this crossword clue is the 9 letter word SISYPHEAN which also is the latest solution we found used in Boston Globe in 2001.
Futile on a grand scale crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| SISYPHEAN | 100 % | 9 | 
Words with a meaning similar to the clue: Futile on a grand scale
These words may or may not be a possible solution to this crosswords clue.- epic
 - big
 - think
 - thunk
 - vig
 - proud
 - palatial
 - epical
 - expansive
 - epos
 - waste
 - barren
 
Crossword Answer definitions
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution