The most common and most likely answer to this crossword clue is the 4 letter word DUNE which also is the latest solution we found used in Newsday in 2001.
Frank Herbert sci-fi opus crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| DUNE | 100 % | 4 | 
Words with a meaning similar to the clue: Frank Herbert sci-fi opus
These words may or may not be a possible solution to this crosswords clue.- dune
 - alien
 - bot
 - pod
 - space
 - nerd
 - ben
 - blast
 - matrix
 - rod
 - tom
 - warp
 
Crossword Answer definitions
DUNE noun- A ridge or hill of sand piled up by the wind.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution