The most common and most likely answer to this crossword clue is the 6 letter word PEYOTE which also is the latest solution we found used in CrossSynergy in 2001.
Dome-shaped cactus crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| PEYOTE | 100 % | 6 | 
Words with a meaning similar to the clue: Dome-shaped cactus
These words may or may not be a possible solution to this crosswords clue.- peyote
 - igloo
 - mescal
 - derby
 - diaphragm
 - mezcal
 - bubble
 - dagoba
 - domed
 - iglu
 - lodge
 - ovenbird
 
Crossword Answer definitions
PEYOTE noun- A small, spineless cactus (Lophophora williamsii) found from southwest United States to central Mexico that produces buttonlike tubercles that can be chewed for its psychedelic effect, primarily from the drug mescaline.
 - A mescal button produced by the plant.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution