The most common and most likely answer to this crossword clue is the 3 letter word IKE which also is the latest solution we found used in New York Times in 2017.
DDE, familiarly crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| IKE | 100 % | 3 | 
Words with a meaning similar to the clue: DDE, familiarly
These words may or may not be a possible solution to this crosswords clue.- doc
 - hep
 - acquainted
 - bossy
 - cat
 - commune
 - comune
 - crack
 - familiarize
 - free
 - goodman
 - hobnob
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution