The most common and most likely answer to this crossword clue is the 6 letter word AREOLE which also is the latest solution we found used in LA Times in 2017.
Cactus spine source crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| AREOLE | 100 % | 6 | 
Words with a meaning similar to the clue: Cactus spine source
These words may or may not be a possible solution to this crosswords clue.- mescal
 - mezcal
 - peyote
 - lophophora williamsii
 - sacred mushroom
 - magic mushroom
 - mescal button
 - thorn
 - booklouse
 - hybrid
 - lyrebird
 - saka
 
Crossword Answer definitions
AREOLE noun- The smallest enclosures created by the veins of a leaf.
 - Bump on a cactus out of which grow clusters of spines.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution