The most common and most likely answer to this crossword clue is the 9 letter word CRAPSHOOT which also is the latest solution we found used in New York Times in 2012.
*Big gamble crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| CRAPSHOOT | 100 % | 9 | 
Words with a meaning similar to the clue: *Big gamble
These words may or may not be a possible solution to this crosswords clue.- crapshoot
 - bet
 - cog
 - oscar
 - table
 - flutter
 - fluttering
 - play
 - plunge
 - plunging
 - casino
 - chance
 
Crossword Answer definitions
CRAPSHOOT noun- A game of craps.
 - A venture with a highly risky or unpredictable outcome.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution