The most common and most likely answer to this crossword clue is the 6 letter word SPLEEN which also is the latest solution we found used in LA Times in 2008.
Anatomical source of ill humor? crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| SPLEEN | 100 % | 6 | 
Words with a meaning similar to the clue: Anatomical source of ill humor?
These words may or may not be a possible solution to this crosswords clue.- spleen
 - bile
 - sullen
 - sour
 - cross
 - chagrin
 - tout
 - choler
 - ire
 - high
 - miff
 - flay
 
Crossword Answer definitions
SPLEEN noun- In vertebrates, including humans, a ductless vascular gland, located in the left upper abdomen near the stomach, which destroys old red blood cells, removes debris from the bloodstream, acts as a reservoir of blood, and produces lymphocytes.
 - (except in the set phrase "to vent one's spleen") A bad mood; spitefulness.
 - A sudden motion or action; a fit; a freak; a whim.
 - Melancholy; hypochondriacal affections.
 - A fit of immoderate laughter or merriment.
 
- To dislike.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution