The most common and most likely answer to this crossword clue is the 6 letter word ENTREE which also is the latest solution we found used in New York Times in 1989.
American's main course crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| ENTREE | 100 % | 6 | 
Words with a meaning similar to the clue: American's main course
These words may or may not be a possible solution to this crosswords clue.- entree
 - major
 - alee
 - plate
 - crosscut
 - side dish
 - sidetrack
 - meatloaf
 - accidental
 - aorta
 - current
 - digress
 
Crossword Answer definitions
ENTREE noun- (French Canada) A smaller dish served before the main course of a meal.
 - The main course or main dish of a meal.
 - The act of entering somewhere, or permission to enter; admittance.
 - An introduction or prelude.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution