The most common and most likely answer to this crossword clue is the 4 letter word ALOE which also is the latest solution we found used in New York Times in 2008.
American ___ (Southwest plant) crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| ALOE | 100 % | 4 | 
Words with a meaning similar to the clue: American ___ (Southwest plant)
These words may or may not be a possible solution to this crosswords clue.- yucca
 - pineapple
 - coca
 - pinkroot
 - tomato
 - hippeastrum
 - contrayerva
 - eucharis
 - heliotrope
 - manihot dulcis
 - sweet cassava
 - beef plant
 
Crossword Answer definitions
ALOE noun- (in the plural) The resins of the tree Aquilaria malaccensis (syn. Aquilaria agallocha), known for their fragrant aroma, produced after infection by the fungus Phialophora parasitica.
 - A plant of the genus Aloe.
 - A strong, bitter drink made from the juice of such plants, used as a purgative.
 
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution