The most common and most likely answer to this crossword clue is the 8 letter word HITSHOME which also is the latest solution we found used in CrossSynergy in 2008.
Affects one directly crossword clue answers
Here's a list of possible crossword answers ranked by the most likely to least likely.
| Answer | Likelyness | Letters | 
|---|---|---|
| HITSHOME | 100 % | 8 | 
Words with a meaning similar to the clue: Affects one directly
These words may or may not be a possible solution to this crosswords clue.- frog
 - face
 - point of honor
 - oligopoly
 - smell
 - conscience
 - active
 - buffet
 - ear
 - experience
 - shoulder
 - cable
 
Crossword Answer definitions
More crossword clues leading to the same solutions
Here's a few more crossword clues - all leading to the identical solution